NR2E1 Antikörper (Internal Region)

Produktnummer ABIN6263720

Produktdetails anti-NR2E1 Antikörper

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR2E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: NR2E1 Antibody detects endogenous levels of total NR2E1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NR2E1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NR2E1

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Andere Bezeichnung: NR2E1 (NR2E1 Produkte)

Synonyme: NR2E1 antikoerper, TLL antikoerper, TLX antikoerper, XTLL antikoerper, Mtl1 antikoerper, Mtll antikoerper, Tlx antikoerper, fierce antikoerper, frc antikoerper, tailless antikoerper, fc30e03 antikoerper, fc39f12 antikoerper, wu:fc30e03 antikoerper, wu:fc39f12 antikoerper, zgc:100991 antikoerper, Xtll antikoerper, nr2e1-A antikoerper, tlx antikoerper, nuclear receptor subfamily 2 group E member 1 antikoerper, nuclear receptor subfamily 2, group E, member 1 antikoerper, nuclear receptor subfamily 2 group E member 1 S homeolog antikoerper, NR2E1 antikoerper, Nr2e1 antikoerper, nr2e1 antikoerper, nr2e1.S antikoerper

Hintergrund:

Description: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells.

Gene: NR2E1

Molekulargewicht: 43 kDa

Gen-ID: 7101

UniProt: Q9Y466

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance