Neuroligin 2 Antikörper

Produktnummer ABIN6263654

Produktdetails anti-Neuroligin 2 Antikörper

Target: Neuroligin 2 (NLGN2)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuroligin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: NLGN2 Antibody detects endogenous levels of total NLGN2

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NLGN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu Neuroligin 2

Target: Neuroligin 2 (NLGN2)

Andere Bezeichnung: NLGN2 (NLGN2 Produkte)

Synonyme: Nlgn2 antikoerper, GB10066 antikoerper, NLGN2 antikoerper, CCE-L2 antikoerper, NV50031 antikoerper, Nv123771 antikoerper, NL2 antikoerper, RP23-422L16.24 antikoerper, neuroligin 2 antikoerper, LOC410779 antikoerper, NLGN2 antikoerper, LOC663865 antikoerper, LOC100123771 antikoerper, Nlgn2 antikoerper

Hintergrund:

Description: Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing. Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion (By similarity).

Gene: NLGN2

Molekulargewicht: 91 kDa

Gen-ID: 57555

UniProt: Q8NFZ4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane