MRC2 Antikörper (N-Term)

Produktnummer ABIN6263346

Produktdetails anti-MRC2 Antikörper

Target: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: MRC2 Antibody detects endogenous levels of total MRC2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MRC2, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MRC2

Target: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Andere Bezeichnung: MRC2 (MRC2 Produkte)

Synonyme: MRC2 antikoerper, cd280 antikoerper, uparap antikoerper, clec13e antikoerper, endo180 antikoerper, Endo180 antikoerper, CD280 antikoerper, CLEC13E antikoerper, ENDO180 antikoerper, UPARAP antikoerper, mKIAA0709 antikoerper, uPARAP antikoerper, mannose receptor C type 2 antikoerper, mannose receptor, C type 2 antikoerper, MRC2 antikoerper, mrc2 antikoerper, Mrc2 antikoerper

Hintergrund:

Description: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Gene: MRC2

Molekulargewicht: 167kDa

Gen-ID: 9902

UniProt: Q9UBG0