MALT1 Antikörper (Internal Region)

Produktnummer ABIN6263086

Produktdetails anti-MALT1 Antikörper

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MALT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Spezifität: MALT1 Antibody detects endogenous levels of total MALT1.

Homologie: Pig,Horse,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MALT1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MALT1

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Andere Bezeichnung: MALT1 (MALT1 Produkte)

Synonyme: malt1 antikoerper, MALT1 antikoerper, mlt antikoerper, mlt1 antikoerper, MLT antikoerper, MLT1 antikoerper, A630046N12 antikoerper, D430033E09Rik antikoerper, MALT paracaspase 2 antikoerper, MALT1 paracaspase antikoerper, MALT1 paracaspase S homeolog antikoerper, paracaspase 3 antikoerper, malt2 antikoerper, MALT1 antikoerper, malt1.S antikoerper, Malt1 antikoerper, PCASP3 antikoerper

Hintergrund:

Description: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Gene: MALT1

Molekulargewicht: 92kDa

Gen-ID: 10892

UniProt: Q9UDY8

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine