LIG3 Antikörper (Internal Region)

Produktnummer ABIN6262966

Produktdetails anti-LIG3 Antikörper

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: DNA Ligase III Antibody detects endogenous levels of total DNA Ligase III.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DNA Ligase III, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Andere Bezeichnung: LIG3 (LIG3 Produkte)

Synonyme: orf36 antikoerper, DDBDRAFT_0218523 antikoerper, DDBDRAFT_0232266 antikoerper, DDB_0218523 antikoerper, DDB_0232266 antikoerper, LIG3 antikoerper, wu:fb12c02 antikoerper, wu:fd10b03 antikoerper, wu:fm79b09 antikoerper, LIG2 antikoerper, D11Wsu78e antikoerper, An02g06890 antikoerper, AO090003000668 antikoerper, lig3 antikoerper, DNA ligase III antikoerper, BRCT domain-containing protein antikoerper, DNA ligase 3 antikoerper, ligase III, DNA, ATP-dependent antikoerper, ligase III, DNA, ATP-dependent L homeolog antikoerper, orf36 antikoerper, lig3 antikoerper, LIG3 antikoerper, Lig3 antikoerper, Bm1_22840 antikoerper, ANI_1_2644024 antikoerper, AOR_1_1174154 antikoerper, LOC100634887 antikoerper, lig3.L antikoerper

Hintergrund:

Description: Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).

Gene: LIG3

Molekulargewicht: 113kDa

Gen-ID: 3980

UniProt: P49916

Pathways: DNA Reparatur