IL31RA Antikörper (Internal Region)

Produktnummer ABIN6262566

Produktdetails anti-IL31RA Antikörper

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL31RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: IL31R Antibody detects endogenous levels of total IL31R.

Homologie: Pig,Bovine,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL31R, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu IL31RA

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Andere Bezeichnung: IL31RA (IL31RA Produkte)

Synonyme: IL31RA antikoerper, CRL antikoerper, CRL3 antikoerper, GLM-R antikoerper, GLMR antikoerper, GPL antikoerper, IL-31RA antikoerper, PLCA2 antikoerper, PRO21384 antikoerper, hGLM-R antikoerper, Glmr antikoerper, NR10 antikoerper, interleukin 31 receptor A antikoerper, IL31RA antikoerper, Il31ra antikoerper

Hintergrund:

Description: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).

Gene: IL31RA

Molekulargewicht: 83 kDa

Gen-ID: 133396

UniProt: Q8NI17