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IL-6 Antikörper (Internal Region)

IL6 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262529
  • Target Alle IL-6 (IL6) Antikörper anzeigen
    IL-6 (IL6) (Interleukin 6 (IL6))
    Bindungsspezifität
    • 19
    • 17
    • 15
    • 15
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 182
    • 135
    • 73
    • 28
    • 22
    • 21
    • 15
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    Human, Maus, Ratte
    Wirt
    • 195
    • 84
    • 72
    • 13
    • 4
    • 3
    • 2
    Kaninchen
    Klonalität
    • 215
    • 155
    • 1
    Polyklonal
    Konjugat
    • 200
    • 63
    • 27
    • 12
    • 11
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-6 Antikörper ist unkonjugiert
    Applikation
    • 267
    • 139
    • 105
    • 62
    • 52
    • 50
    • 41
    • 41
    • 38
    • 31
    • 25
    • 25
    • 22
    • 20
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    IL6 Antibody detects endogenous levels of total IL6.
    Homologie
    Bovine
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IL6, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product IL6 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Yi, Shen, Zhao, Shao, Liu, Cui, Wang, Wang, Guo, Kang, Lv, Xing, Zhang: "Inflammation-mediated SOD-2 upregulation contributes to epithelial-mesenchymal transition and migration of tumor cells in aflatoxin G1-induced lung adenocarcinoma." in: Scientific reports, Vol. 7, Issue 1, pp. 7953, (2018) (PubMed).

    Ji, Zheng, Liu, Ren, Gao, Zhang, Li: "Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells." in: Experimental cell research, Vol. 370, Issue 2, pp. 292-302, (2018) (PubMed).

  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Andere Bezeichnung
    IL6 (IL6 Produkte)
    Synonyme
    BSF2 antikoerper, HGF antikoerper, HSF antikoerper, IFNB2 antikoerper, IL-6 antikoerper, Il-6 antikoerper, ILg6 antikoerper, Ifnb2 antikoerper, il6 antikoerper, CHIL-6 antikoerper, interleukin 6 antikoerper, interleukin-6 antikoerper, IL6 antikoerper, Il6 antikoerper, il-6 antikoerper, IL-6 antikoerper
    Hintergrund

    Description: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

    Gene: IL6

    Molekulargewicht
    24kDa
    Gen-ID
    3569
    UniProt
    P05231
    Pathways
    TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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