IFITM2 Antikörper

Produktnummer ABIN6262458

Produktdetails anti-IFITM2 Antikörper

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFITM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: IFM2 Antibody detects endogenous levels of total IFM2

Kreuzreaktivität: Human

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IFM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu IFITM2

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Andere Bezeichnung: IFM2 (IFITM2 Produkte)

Synonyme: 1-8D antikoerper, DSPA2c antikoerper, Ifitm3l antikoerper, fragilis3 antikoerper, mil-3 antikoerper, Ifitml antikoerper, interferon induced transmembrane protein 2 antikoerper, IFITM2 antikoerper, Ifitm2 antikoerper

Hintergrund:

Description: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Gene: IFITM2

Molekulargewicht: 14 kDa

Gen-ID: 10581

UniProt: Q01629, P13164, Q01628