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HSP27 Antikörper (Internal Region)

Name: HSP27 Antikörper (Internal Region)
SKU: ABIN6262392
Price: 698.46 EUR
Availability: InStock

HSPB1 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of HSP27 expression in Ca2+ treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

ABIN6269087 at 1/100 staining Mouse pancreas tissue by IHC-P.

IHC

IF/ICC

3 Abbildungen

(1 reference)

Produktnummer ABIN6262392

Datenblatt (PDF)

Target Alle HSP27 (HSPB1) Antikörper anzeigen

HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
Bindungsspezifität
42

37

27

16

16

10

8

8

7

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
Reaktivität
299

104

90

24

14

14

13

12

11

6

6

4

3

2

2

2

1
Human, Ratte, Maus
Wirt
237

66
Kaninchen
Passende Sekundärantikörper
Klonalität
206

96
Polyklonal
Konjugat
138

23

17

13

12

8

7

7

7

7

7

7

4

4

4

4

4

4

4

3

3

3

3

2

1

1

1

1

1

1

1

1
Dieser HSP27 Antikörper ist unkonjugiert
Applikation
256

103

103

95

69

49

49

46

41

40

16

12

10

7

7

2

2

2

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität

HSP27 Antibody detects endogenous levels of total HSP27.

Homologie

Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Xenopus

Aufreinigung

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human HSP27, corresponding to a region within the internal amino acids.

Isotyp

IgG

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anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 96-205) antibody
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anti-Heat Shock 27kDa Protein 1 (HSPB1) antibody
HSPB1 Reaktivität: Human WB, IHC, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Heat Shock 27kDa Protein 1 (HSPB1) antibody
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anti-Heat Shock 27kDa Protein 1 (HSPB1) antibody (HRP)
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Applikationshinweise

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit

12 months
Xia, Yao, Tang, Xiao, Yang, Zhou: "Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Hugan Qingzhi and Its Protective Properties against Free Fatty Acid-Induced L02 Hepatocyte Injury." in: Frontiers in pharmacology, Vol. 8, pp. 99, (2017) (PubMed).
Target

HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Andere Bezeichnung

HSPB1 (HSPB1 Produkte)

Synonyme

CMT2F antikoerper, HMN2B antikoerper, HS.76067 antikoerper, HSP27 antikoerper, HSP28 antikoerper, Hsp25 antikoerper, SRP27 antikoerper, 27kDa antikoerper, Hsp27 antikoerper, cb153 antikoerper, cb660 antikoerper, hsp1 antikoerper, hsp25 antikoerper, hsp27 antikoerper, id:ibd2821 antikoerper, sb:cb660 antikoerper, zgc:103437 antikoerper, HSPB1 antikoerper, cmt2f antikoerper, hs.76067 antikoerper, hsp28 antikoerper, heat shock protein family B (small) member 1 antikoerper, heat shock protein 1 antikoerper, heat shock protein, alpha-crystallin-related, 1 antikoerper, heat shock protein family B (small) member 1 L homeolog antikoerper, HSPB1 antikoerper, Hspb1 antikoerper, hspb1 antikoerper, hspb1.L antikoerper

Hintergrund

Description: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).
Gene: HSPB1

Molekulargewicht

27kDa

Gen-ID

3315

UniProt

P04792

Pathways

MAPK Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling