Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HEY1 Antikörper (Internal Region)

HEY1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262226
  • Target Alle HEY1 Antikörper anzeigen
    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 26
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 18
    • 7
    • 1
    Kaninchen
    Klonalität
    • 20
    • 6
    Polyklonal
    Konjugat
    • 22
    • 2
    • 1
    • 1
    Dieser HEY1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    HEY1 Antibody detects endogenous levels of total HEY1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HEY1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product HEY1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))
    Andere Bezeichnung
    HEY1 (HEY1 Produkte)
    Synonyme
    BHLHb31 antikoerper, CHF2 antikoerper, HERP2 antikoerper, HESR1 antikoerper, HRT-1 antikoerper, OAF1 antikoerper, AI316788 antikoerper, AI414254 antikoerper, HRT1 antikoerper, Herp2 antikoerper, Hesr1 antikoerper, bHLHb31 antikoerper, hesr-1 antikoerper, id:ibd1292 antikoerper, zgc:110572 antikoerper, bc8 antikoerper, chf2 antikoerper, herp2 antikoerper, hesr1 antikoerper, hrt1 antikoerper, oaf1 antikoerper, xbc8 antikoerper, hes related family bHLH transcription factor with YRPW motif 1 antikoerper, hairy/enhancer-of-split related with YRPW motif 1 antikoerper, hes-related family bHLH transcription factor with YRPW motif 1 antikoerper, hes related family bHLH transcription factor with YRPW motif 1 S homeolog antikoerper, HEY1 antikoerper, Hey1 antikoerper, hey1 antikoerper, hey1.S antikoerper
    Hintergrund

    Description: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).

    Gene: HEY1

    Molekulargewicht
    32-34 kDa
    Gen-ID
    23462
    UniProt
    Q9Y5J3
    Pathways
    Tube Formation
Sie sind hier:
Kundenservice