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GEMIN8 Antikörper (C-Term)

GEMIN8 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261938
  • Target Alle GEMIN8 Antikörper anzeigen
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Bindungsspezifität
    • 8
    • 6
    • 6
    • 5
    C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 29
    • 2
    Kaninchen
    Klonalität
    • 29
    • 2
    Polyklonal
    Konjugat
    • 10
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GEMIN8 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 17
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    GEMIN8 Antibody detects endogenous levels of total GEMIN8.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GEMIN8, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product GEMIN8 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Andere Bezeichnung
    GEMIN8 (GEMIN8 Produkte)
    Synonyme
    FAM51A1 antikoerper, B130034M20Rik antikoerper, B930082C09Rik antikoerper, BC023488 antikoerper, gemin-8 antikoerper, gem nuclear organelle associated protein 8 antikoerper, gemin8 antikoerper, GEMIN8 antikoerper, Gemin8 antikoerper
    Hintergrund

    Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

    Gene: GEMIN8

    Molekulargewicht
    29kDa
    Gen-ID
    54960
    UniProt
    Q9NWZ8
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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