GAS8 Antikörper (Internal Region)

Produktnummer ABIN6261889

Produktdetails anti-GAS8 Antikörper

Target: GAS8 (Growth Arrest-Specific 8 (GAS8))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAS8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Spezifität: GAS8 Antibody detects endogenous levels of total GAS8.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GAS8, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GAS8

Target: GAS8 (Growth Arrest-Specific 8 (GAS8))

Andere Bezeichnung: GAS8 (GAS8 Produkte)

Synonyme: CG14271 antikoerper, Dmel\\CG14271 antikoerper, zgc:66271 antikoerper, wu:fb93e12 antikoerper, MGC114774 antikoerper, Gas11 antikoerper, GAS11 antikoerper, Growth arrest specific protein 8 antikoerper, growth arrest-specific 8 antikoerper, growth arrest specific 8 antikoerper, growth arrest specific 8 S homeolog antikoerper, Gas8 antikoerper, gas8 antikoerper, GAS8 antikoerper, gas8.S antikoerper

Hintergrund:

Description: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning (PubMed:26387594, PubMed:27120127, PubMed:27472056). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner (By similarity).

Gene: GAS8

Molekulargewicht: 56 kDa

Gen-ID: 2622

UniProt: O95995