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EPH Receptor A8 Antikörper (Internal Region)

EPHA8 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261567
  • Target Alle EPH Receptor A8 (EPHA8) Antikörper anzeigen
    EPH Receptor A8 (EPHA8)
    Bindungsspezifität
    • 7
    • 7
    • 4
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 25
    • 16
    • 1
    Human
    Wirt
    • 24
    • 1
    Kaninchen
    Klonalität
    • 24
    • 1
    Polyklonal
    Konjugat
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser EPH Receptor A8 Antikörper ist unkonjugiert
    Applikation
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    EPHA8 Antibody detects endogenous levels of total EPHA8.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human EPHA8, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product EPHA8 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    EPH Receptor A8 (EPHA8)
    Andere Bezeichnung
    EPHA8 (EPHA8 Produkte)
    Synonyme
    TK antikoerper, tke17-a antikoerper, si:ch211-122l14.1 antikoerper, EPHA8 antikoerper, EEK antikoerper, EK3 antikoerper, HEK3 antikoerper, AW047546 antikoerper, Eek antikoerper, Hek3 antikoerper, mKIAA1459 antikoerper, EPH receptor A8 L homeolog antikoerper, EPH receptor A8 antikoerper, eph receptor A8 antikoerper, Eph receptor A8 antikoerper, epha8.L antikoerper, EPHA8 antikoerper, epha8 antikoerper, Epha8 antikoerper
    Hintergrund

    Description: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth (By similarity).

    Gene: EPHA8

    Molekulargewicht
    111kDa.
    Gen-ID
    2046
    UniProt
    P29322
    Pathways
    RTK Signalweg
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