EPH Receptor A8 Antikörper (Internal Region)
-
- Target Alle EPH Receptor A8 (EPHA8) Antikörper anzeigen
- EPH Receptor A8 (EPHA8)
-
Bindungsspezifität
- Internal Region
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser EPH Receptor A8 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Spezifität
- EPHA8 Antibody detects endogenous levels of total EPHA8.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human EPHA8, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product EPHA8 Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
-
- Target
- EPH Receptor A8 (EPHA8)
- Andere Bezeichnung
- EPHA8 (EPHA8 Produkte)
- Synonyme
- TK antikoerper, tke17-a antikoerper, si:ch211-122l14.1 antikoerper, EPHA8 antikoerper, EEK antikoerper, EK3 antikoerper, HEK3 antikoerper, AW047546 antikoerper, Eek antikoerper, Hek3 antikoerper, mKIAA1459 antikoerper, EPH receptor A8 L homeolog antikoerper, EPH receptor A8 antikoerper, eph receptor A8 antikoerper, Eph receptor A8 antikoerper, epha8.L antikoerper, EPHA8 antikoerper, epha8 antikoerper, Epha8 antikoerper
- Hintergrund
-
Description: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth (By similarity).
Gene: EPHA8
- Molekulargewicht
- 111kDa.
- Gen-ID
- 2046
- UniProt
- P29322
- Pathways
- RTK Signalweg
-