DVL1 Antikörper

Produktnummer ABIN6261389

Produktdetails anti-DVL1 Antikörper

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DVL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: DVL1 Antibody detects endogenous levels of total DVL1

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DVL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000 IHC 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu DVL1

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Andere Bezeichnung: DVL1 (DVL1 Produkte)

Synonyme: DVL antikoerper, DVL1L1 antikoerper, DVL1P1 antikoerper, Dvl antikoerper, mKIAA4029 antikoerper, dvl-1 antikoerper, DSH antikoerper, DVL-1 antikoerper, dvl1 antikoerper, dvl2l antikoerper, Xdsh antikoerper, dsh1 antikoerper, dishevelled segment polarity protein 1 antikoerper, dishevelled, dsh homolog 1 (Drosophila) antikoerper, microRNA 6808 antikoerper, dishevelled segment polarity protein 1b antikoerper, dishevelled segment polarity protein 1 L homeolog antikoerper, DVL1 antikoerper, Dvl1 antikoerper, MIR6808 antikoerper, dvl1b antikoerper, dvl1.L antikoerper

Hintergrund:

Description: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Gene: DVL1

Molekulargewicht: 75 kDa

Gen-ID: 1855

UniProt: O14640

Pathways: WNT Signalweg, Synaptic Membrane, Skeletal Muscle Fiber Development