DAAM1 Antikörper (Internal Region)

Produktnummer ABIN6261212

Produktdetails anti-DAAM1 Antikörper

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: DAAM1 Antibody detects endogenous levels of total DAAM1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DAAM1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DAAM1

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Andere Bezeichnung: DAAM1 (DAAM1 Produkte)

Synonyme: 1700066F09Rik antikoerper, 2310028E21Rik antikoerper, AI503486 antikoerper, E130308H01 antikoerper, mKIAA0666 antikoerper, daam-1 antikoerper, xdaam1 antikoerper, daam1 antikoerper, DAAM1 antikoerper, DKFZp468D0524 antikoerper, daam1l antikoerper, fc83b10 antikoerper, si:ch211-87i20.1 antikoerper, wu:fc83b10 antikoerper, dishevelled associated activator of morphogenesis 1 antikoerper, dishevelled associated activator of morphogenesis 1 S homeolog antikoerper, dishevelled associated activator of morphogenesis 1a antikoerper, dishevelled associated activator of morphogenesis 1b antikoerper, DAAM1 antikoerper, Daam1 antikoerper, daam1.S antikoerper, daam1a antikoerper, daam1 antikoerper, daam1b antikoerper

Hintergrund:

Description: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). Together with DAAM2, required for myocardial maturation and sarcomere assembly (By similarity).

Gene: DAAM1

Molekulargewicht: 123 kDa

Gen-ID: 23002

UniProt: Q9Y4D1

Pathways: WNT Signalweg