CYP4F2 Antikörper (N-Term)

Produktnummer ABIN6261173

Produktdetails anti-CYP4F2 Antikörper

Target: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP4F2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: CYP4F2 Antibody detects endogenous levels of total CYP4F2.

Homologie: Pig,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CYP4F2, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CYP4F2

Target: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Andere Bezeichnung: CYP4F2 (CYP4F2 Produkte)

Synonyme: CPF2 antikoerper, MGC126966 antikoerper, cytochrome P450 family 4 subfamily F member 2 antikoerper, cytochrome P450, family 4, subfamily F, polypeptide 2 antikoerper, cytochrome P450 family 4 subfamily F member 2 L homeolog antikoerper, CYP4F2 antikoerper, cyp4f2.L antikoerper

Hintergrund:

Description: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B4 omega-hydroxylase by mediating conversion of leukotriene-B4 (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B4 (20-OH LTB4) (PubMed:8026587, PubMed:9799565).

Gene: CYP4F2

Molekulargewicht: 60kDa

Gen-ID: 8529

UniProt: P78329

Pathways: Monocarboxylic Acid Catabolic Process