CYFIP1 Antikörper (Internal Region)

Produktnummer ABIN6261160

Produktdetails anti-CYFIP1 Antikörper

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYFIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CYFIP1 Antibody detects endogenous levels of total CYFIP1.

Homologie: Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CYFIP1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CYFIP1

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Andere Bezeichnung: CYFIP1 (CYFIP1 Produkte)

Synonyme: TUBGCP5 antikoerper, P140SRA-1 antikoerper, SHYC antikoerper, SRA1 antikoerper, E030028J09Rik antikoerper, P140sra1 antikoerper, Shyc antikoerper, Sra-1 antikoerper, Sra1 antikoerper, l(7)1Rl antikoerper, l71Rl antikoerper, l7Rl1 antikoerper, mKIAA0068 antikoerper, pl-1 antikoerper, CY antikoerper, CYFIP antikoerper, fb15a06 antikoerper, wu:fb15a06 antikoerper, cytoplasmic FMR1 interacting protein 1 antikoerper, CYFIP1 antikoerper, cyfip1 antikoerper, Cyfip1 antikoerper

Hintergrund:

Description: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.

Gene: CYFIP1

Molekulargewicht: 145 kDa

Gen-ID: 23191

UniProt: Q7L576