CXXC5 Antikörper
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- Target Alle CXXC5 Antikörper anzeigen
- CXXC5 (CXXC Finger Protein 5 (CXXC5))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CXXC5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- CXXC5 antibody detects endogenous levels of CXXC5.
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CXXC5.
- Isotyp
- IgG
- Top Product
- Discover our top product CXXC5 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- CXXC5 (CXXC Finger Protein 5 (CXXC5))
- Andere Bezeichnung
- CXXC5 (CXXC5 Produkte)
- Synonyme
- 4930415K17Rik antikoerper, CF5 antikoerper, RINF antikoerper, WID antikoerper, CXXC finger 5 antikoerper, CXXC finger protein 5 antikoerper, Cxxc5 antikoerper, CXXC5 antikoerper
- Hintergrund
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Description: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4 % oxygen), as well as normoxia conditions (20 % oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788).
Gene: CXXC5
- Molekulargewicht
- 35-40 kDa
- Gen-ID
- 51523
- UniProt
- Q7LFL8
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