C-Type Lectin Domain Family 6, Member A (CLEC6A) (Internal Region) Antikörper
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- Target Alle C-Type Lectin Domain Family 6, Member A (CLEC6A) Antikörper anzeigen
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- CLEC6A Antibody detects endogenous levels of total CLEC6A.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CLEC6A, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CLEC6A Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
- Andere Bezeichnung
- CLEC6A (CLEC6A Produkte)
- Synonyme
- CLEC4N antikoerper, CLECSF10 antikoerper, CLEC6A antikoerper, C-type lectin domain containing 6A antikoerper, C-type lectin domain family 6, member A antikoerper, CLEC6A antikoerper, Clec6a antikoerper
- Hintergrund
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Description: Binds high-mannose carbohydrates in a Ca2+-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway (By similarity).
Gene: CLEC6A
- Molekulargewicht
- 24 kDa
- Gen-ID
- 93978
- UniProt
- Q6EIG7
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