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CITED1 Antikörper (Internal Region)

CITED1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260846
  • Target Alle CITED1 Antikörper anzeigen
    CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
    Bindungsspezifität
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 27
    • 18
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 20
    • 8
    Kaninchen
    Klonalität
    • 20
    • 8
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CITED1 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    CITED1 Antibody detects endogenous levels of total CITED1.
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CITED1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CITED1 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
    Andere Bezeichnung
    CITED1 (CITED1 Produkte)
    Synonyme
    cited1 antikoerper, fi05d05 antikoerper, CITED1 antikoerper, MSG1 antikoerper, AI316840 antikoerper, AU019144 antikoerper, Msg1 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 antikoerper, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 antikoerper, similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) antikoerper, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 antikoerper, cited1 antikoerper, CITED1 antikoerper, Cited1 antikoerper
    Hintergrund

    Description: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.

    Gene: CITED1

    Molekulargewicht
    20 kDa
    Gen-ID
    4435
    UniProt
    Q99966
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