CHI3L1 Antikörper (Internal Region)
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- Target Alle CHI3L1 Antikörper anzeigen
- CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHI3L1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- CHI3L1 Antibody detects endogenous levels of total CHI3L1.
- Homologie
- Pig,Bovine,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CHI3L1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CHI3L1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
- Andere Bezeichnung
- CHI3L1 (CHI3L1 Produkte)
- Synonyme
- AW208766 antikoerper, Brp39 antikoerper, Gp39 antikoerper, ASRT7 antikoerper, CGP-39 antikoerper, GP-39 antikoerper, GP39 antikoerper, HC-gp39 antikoerper, HCGP-3P antikoerper, YKL-40 antikoerper, YKL40 antikoerper, YYL-40 antikoerper, hCGP-39 antikoerper, GP38K antikoerper, CLP-1 antikoerper, SPC-40 antikoerper, SPS-40 antikoerper, Chil1 antikoerper, BP40 antikoerper, MGP-40 antikoerper, chitinase-like 1 antikoerper, chitinase 3 like 1 antikoerper, chitinase 3-like 1 (cartilage glycoprotein-39) antikoerper, Chil1 antikoerper, CHI3L1 antikoerper, Chi3l1 antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
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Description: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
Gene: CHI3L1
- Molekulargewicht
- 43kDa
- Gen-ID
- 1116
- UniProt
- P36222
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