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CHI3L1 Antikörper (Internal Region)

CHI3L1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260803
  • Target Alle CHI3L1 Antikörper anzeigen
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    Bindungsspezifität
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 43
    • 29
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 41
    • 5
    • 1
    Kaninchen
    Klonalität
    • 41
    • 5
    • 1
    Polyklonal
    Konjugat
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHI3L1 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 15
    • 13
    • 13
    • 10
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    CHI3L1 Antibody detects endogenous levels of total CHI3L1.
    Homologie
    Pig,Bovine,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CHI3L1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CHI3L1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    Andere Bezeichnung
    CHI3L1 (CHI3L1 Produkte)
    Synonyme
    AW208766 antikoerper, Brp39 antikoerper, Gp39 antikoerper, ASRT7 antikoerper, CGP-39 antikoerper, GP-39 antikoerper, GP39 antikoerper, HC-gp39 antikoerper, HCGP-3P antikoerper, YKL-40 antikoerper, YKL40 antikoerper, YYL-40 antikoerper, hCGP-39 antikoerper, GP38K antikoerper, CLP-1 antikoerper, SPC-40 antikoerper, SPS-40 antikoerper, Chil1 antikoerper, BP40 antikoerper, MGP-40 antikoerper, chitinase-like 1 antikoerper, chitinase 3 like 1 antikoerper, chitinase 3-like 1 (cartilage glycoprotein-39) antikoerper, Chil1 antikoerper, CHI3L1 antikoerper, Chi3l1 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund

    Description: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

    Gene: CHI3L1

    Molekulargewicht
    43kDa
    Gen-ID
    1116
    UniProt
    P36222
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