CD320 Antikörper (Internal Region)

Produktnummer ABIN6260613

Produktdetails anti-CD320 Antikörper

Target: CD320 (CD320 Molecule (CD320))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD320 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CD320 Antibody detects endogenous levels of total CD320.

Homologie: Bovine,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CD320, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CD320

Target: CD320 (CD320 Molecule (CD320))

Andere Bezeichnung: CD320 (CD320 Produkte)

Synonyme: 8D6 antikoerper, 8D6A antikoerper, TCBLR antikoerper, 425O18-1 antikoerper, D17Ertd716e antikoerper, NG29 antikoerper, VLDL antikoerper, RGD1305860 antikoerper, TCblR antikoerper, CD320 molecule antikoerper, CD320 antigen antikoerper, CD320 antikoerper, Cd320 antikoerper

Hintergrund:

Description: Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213). Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed:10727470). Functions as costimulator to promote B cell responses to antigenic stimuli, promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631). Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed:11418631). CD320 augments the proliferation of PC precursors generated by IL-10 (PubMed:11418631).

Gene: CD320

Molekulargewicht: 29kDa

Gen-ID: 51293

UniProt: Q9NPF0