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ATXN7L3 Antikörper (Internal Region)

ATXN7L3 Reaktivität: Human, Maus ELISA, WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260152
  • Target Alle ATXN7L3 Antikörper anzeigen
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 18
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATXN7L3 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    ATXN7L3 Antibody detects endogenous levels of total ATXN7L3.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ATXN7L3, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ATXN7L3 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    Andere Bezeichnung
    ATXN7L3 (ATXN7L3 Produkte)
    Synonyme
    E030022H21Rik antikoerper, si:busm1-180g5.4 antikoerper, si:dz180g5.4 antikoerper, wu:fj12f07 antikoerper, zgc:136438 antikoerper, zgc:158566 antikoerper, ataxin 7 like 3 antikoerper, ataxin 7-like 3 antikoerper, ATXN7L3 antikoerper, Atxn7l3 antikoerper, atxn7l3 antikoerper
    Hintergrund

    Description: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879). The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972). Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583).

    Gene: ATXN7L3

    Molekulargewicht
    39 kDa
    Gen-ID
    56970
    UniProt
    Q14CW9
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