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ATP8A1 Antikörper (Internal Region)

ATP8A1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260139
  • Target Alle ATP8A1 Antikörper anzeigen
    ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
    Bindungsspezifität
    Internal Region
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 7
    Kaninchen
    Klonalität
    • 7
    Polyklonal
    Konjugat
    • 3
    • 2
    • 1
    • 1
    Dieser ATP8A1 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    ATP8A1 Antibody detects endogenous levels of total ATP8A1.
    Homologie
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ATP8A1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ATP8A1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
    Andere Bezeichnung
    ATP8A1 (ATP8A1 Produkte)
    Synonyme
    ATPASEII antikoerper, ATPIA antikoerper, ATPP2 antikoerper, AI481521 antikoerper, AI853962 antikoerper, APLT antikoerper, AW743152 antikoerper, AW822227 antikoerper, Atp3a2 antikoerper, B230107D19Rik antikoerper, ClassI antikoerper, mKIAA4233 antikoerper, ATPase phospholipid transporting 8A1 antikoerper, ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 antikoerper, Atp8a1 antikoerper, ATP8A1 antikoerper
    Hintergrund

    Description: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

    Gene: ATP8A1

    Molekulargewicht
    120 kDa
    Gen-ID
    10396
    UniProt
    Q9Y2Q0
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