ATP8A1 Antikörper (Internal Region)
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- Target Alle ATP8A1 Antikörper anzeigen
- ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
- Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATP8A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- ATP8A1 Antibody detects endogenous levels of total ATP8A1.
- Homologie
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ATP8A1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ATP8A1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
- Andere Bezeichnung
- ATP8A1 (ATP8A1 Produkte)
- Synonyme
- ATPASEII antikoerper, ATPIA antikoerper, ATPP2 antikoerper, AI481521 antikoerper, AI853962 antikoerper, APLT antikoerper, AW743152 antikoerper, AW822227 antikoerper, Atp3a2 antikoerper, B230107D19Rik antikoerper, ClassI antikoerper, mKIAA4233 antikoerper, ATPase phospholipid transporting 8A1 antikoerper, ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 antikoerper, Atp8a1 antikoerper, ATP8A1 antikoerper
- Hintergrund
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Description: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.
Gene: ATP8A1
- Molekulargewicht
- 120 kDa
- Gen-ID
- 10396
- UniProt
- Q9Y2Q0
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