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ARF1 Antikörper (Internal Region)

ARF1 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260020
  • Target Alle ARF1 Antikörper anzeigen
    ARF1 (ADP-Ribosylation Factor 1 (ARF1))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 68
    • 40
    • 26
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 69
    • 14
    • 1
    Kaninchen
    Klonalität
    • 62
    • 22
    Polyklonal
    Konjugat
    • 35
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARF1 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 36
    • 29
    • 17
    • 13
    • 13
    • 11
    • 11
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    ARF1 Antibody detects endogenous levels of total ARF1.
    Homologie
    Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ARF1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ARF1 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ARF1 (ADP-Ribosylation Factor 1 (ARF1))
    Andere Bezeichnung
    ARF1 (ARF1 Produkte)
    Synonyme
    wu:fb33e02 antikoerper, wu:fb78h01 antikoerper, arf2 antikoerper, arf-1 antikoerper, MGC52573 antikoerper, ADP-RIBOSYLATION FACTOR antikoerper, ADP-RIBOSYLATION FACTOR 1A antikoerper, ADP-ribosylation factor 1 antikoerper, ATARF antikoerper, ATARF1 antikoerper, ATARFA1A antikoerper, F28C11.12 antikoerper, ARF1 antikoerper, arf1 antikoerper, ADP ribosylation factor 1 antikoerper, ADP-ribosylation factor 1 antikoerper, ADP ribosylation factor 1 L homeolog antikoerper, ADP ribosylation factor 5 L homeolog antikoerper, ADP ribosylation factor 1 pseudogene antikoerper, adp-ribosylation factor 1 antikoerper, ARF1 antikoerper, Arf1 antikoerper, arf1 antikoerper, arf1.L antikoerper, arf5.L antikoerper, NCU08340 antikoerper, TRIADDRAFT_63238 antikoerper, PAAG_08805 antikoerper, LOC100280562 antikoerper, LOC100280918 antikoerper, LOC474591 antikoerper, CLUG_01013 antikoerper
    Hintergrund

    Description: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).

    Gene: ARF1

    Molekulargewicht
    20 kDa
    Gen-ID
    375
    UniProt
    P84077
    Pathways
    Transition Metal Ion Homeostasis, Inositol Metabolic Process
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