MIB2 Antikörper (Internal Region)
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- Target Alle MIB2 Antikörper anzeigen
- MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
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Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MIB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- MIB2 Antibody detects endogenous levels of total MIB2.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MIB2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product MIB2 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
- Andere Bezeichnung
- MIB2 (MIB2 Produkte)
- Synonyme
- ZZANK1 antikoerper, ZZZ5 antikoerper, 2210008I11Rik antikoerper, Zzank1 antikoerper, skd antikoerper, mib2 antikoerper, mindbomb E3 ubiquitin protein ligase 2 antikoerper, mindbomb E3 ubiquitin protein ligase 2 S homeolog antikoerper, MIB2 antikoerper, Mib2 antikoerper, mib2 antikoerper, mib2.S antikoerper
- Hintergrund
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
Gene: MIB2
- Molekulargewicht
- ?110 kDa
- Gen-ID
- 142678
- UniProt
- Q96AX9
- Pathways
- Notch Signalweg
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