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MBTPS1 Antikörper (Internal Region)

MBTPS1 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259458
  • Target Alle MBTPS1 Antikörper anzeigen
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    Bindungsspezifität
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Internal Region
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 26
    • 1
    Kaninchen
    Klonalität
    • 26
    • 1
    Polyklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MBTPS1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 8
    • 7
    • 6
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    MBTPS1 Antibody detects endogenous levels of total MBTPS1.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MBTPS1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MBTPS1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    Andere Bezeichnung
    MBTPS1 (MBTPS1 Produkte)
    Synonyme
    PCSK8 antikoerper, S1P antikoerper, SKI-1 antikoerper, 0610038M03Rik antikoerper, AV003995 antikoerper, Ski1 antikoerper, mKIAA0091 antikoerper, S1p antikoerper, Ski-1 antikoerper, membrane bound transcription factor peptidase, site 1 antikoerper, membrane-bound transcription factor peptidase, site 1 antikoerper, MBTPS1 antikoerper, Mbtps1 antikoerper
    Hintergrund

    Description: Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.

    Gene: MBTPS1

    Molekulargewicht
    117 kDa
    Gen-ID
    8720
    UniProt
    Q14703
    Pathways
    ER-Nucleus Signaling
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