TCF7L1 Antikörper (Internal Region)

Produktnummer ABIN6258956

Produktdetails anti-TCF7L1 Antikörper

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF7L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: TCF7L1 Antibody detects endogenous levels of total TCF7L1.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TCF7L1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TCF7L1

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Andere Bezeichnung: TCF7L1 (TCF7L1 Produkte)

Synonyme: TCF-3 antikoerper, TCF3 antikoerper, Tcf-3 antikoerper, Tcf3 antikoerper, bHLHb21 antikoerper, tcf3c antikoerper, tcf3d antikoerper, xtcf3 antikoerper, XTCF-3 antikoerper, tcf7l1 antikoerper, tcf3b antikoerper, TCF-3-A antikoerper, tcf-3 antikoerper, tcf3 antikoerper, tcf3a antikoerper, zTcf-3 antikoerper, transcription factor 7 like 1 antikoerper, transcription factor 7 like 1 (T cell specific, HMG box) antikoerper, transcription factor 7 like 1 L homeolog antikoerper, transcription factor 7 like 1 S homeolog antikoerper, transcription factor 7 like 1b antikoerper, transcription factor 7 like 1a antikoerper, TCF7L1 antikoerper, Tcf7l1 antikoerper, tcf7l1.L antikoerper, tcf7l1.S antikoerper, tcf7l1b antikoerper, tcf7l1a antikoerper

Hintergrund:

Description: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Gene: TCF7L1

Molekulargewicht: 63 kDa

Gen-ID: 83439

UniProt: Q9HCS4

Pathways: WNT Signalweg, Stem Cell Maintenance