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Glucagon Receptor Antikörper (Internal Region)

GCGR Reaktivität: Human, Ratte, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258919
  • Target Alle Glucagon Receptor (GCGR) Antikörper anzeigen
    Glucagon Receptor (GCGR)
    Bindungsspezifität
    • 16
    • 8
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 55
    • 25
    • 24
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Human, Ratte, Maus
    Wirt
    • 53
    • 1
    • 1
    Kaninchen
    Klonalität
    • 54
    • 1
    Polyklonal
    Konjugat
    • 21
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glucagon Receptor Antikörper ist unkonjugiert
    Applikation
    • 40
    • 23
    • 18
    • 13
    • 13
    • 12
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    GLR Antibody detects endogenous levels of total GLR.
    Homologie
    Pig,Bovine,Horse,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GLR, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product GCGR Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Glucagon Receptor (GCGR)
    Andere Bezeichnung
    GCGR (GCGR Produkte)
    Synonyme
    GCGR antikoerper, GGR antikoerper, GR antikoerper, glucagon receptor antikoerper, GCGR antikoerper, Gcgr antikoerper
    Hintergrund

    Description: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

    Gene: GCGR

    Molekulargewicht
    54 kDa
    Gen-ID
    2642
    UniProt
    P47871
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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