GPRC5A Antikörper (Internal Region)

Produktnummer ABIN6258884

Produktdetails anti-GPRC5A Antikörper

Target: GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPRC5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: GPRC5A Antibody detects endogenous levels of total GPRC5A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPRC5A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GPRC5A

Target: GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))

Andere Bezeichnung: GPRC5A (GPRC5A Produkte)

Synonyme: GPCR5A antikoerper, RAI3 antikoerper, RAIG1 antikoerper, Rai3 antikoerper, Raig1 antikoerper, G protein-coupled receptor class C group 5 member A antikoerper, G protein-coupled receptor, family C, group 5, member A antikoerper, G protein-coupled receptor, class C, group 5, member A antikoerper, GPRC5A antikoerper, Gprc5a antikoerper

Hintergrund:

Description: Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling (By similarity). May act as a lung tumor suppressor (PubMed:18000218).

Gene: GPRC5A

Molekulargewicht: 40 kDa

Gen-ID: 9052

UniProt: Q8NFJ5