KCNQ5 Antikörper (C-Term)

Produktnummer ABIN6258866

Produktdetails anti-KCNQ5 Antikörper

Target: KCNQ5 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNQ5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: KCNQ5 Antibody detects endogenous levels of total KCNQ5.

Homologie: Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNQ5, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu KCNQ5

Target: KCNQ5 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5))

Andere Bezeichnung: KCNQ5 (KCNQ5 Produkte)

Synonyme: KCNQ5 antikoerper, si:dkey-29l6.1 antikoerper, Kcnq5l antikoerper, Kv7.5 antikoerper, 7730402H11 antikoerper, 9230107O05Rik antikoerper, AA589396 antikoerper, D1Mgi1 antikoerper, potassium voltage-gated channel subfamily Q member 5 antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 5a antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 5 antikoerper, potassium voltage-gated channel, subfamily Q, member 5 antikoerper, KCNQ5 antikoerper, kcnq5a antikoerper, Kcnq5 antikoerper

Hintergrund:

Description: Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. As the native M-channel, the potassium channel composed of KCNQ3 and KCNQ5 is also suppressed by activation of the muscarinic acetylcholine receptor CHRM1.

Gene: KCNQ5

Molekulargewicht: 100 kDa

Gen-ID: 56479

UniProt: Q9NR82