CD2AP Antikörper (Internal Region)

Produktnummer ABIN6258700

Produktdetails anti-CD2AP Antikörper

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD2AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: CD2AP Antibody detects endogenous levels of total CD2AP.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CD2AP, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CD2AP

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Andere Bezeichnung: CD2AP (Cd2ap Produkte)

Synonyme: cd2apl antikoerper, fj51c01 antikoerper, im:7153970 antikoerper, si:ch211-207n9.1 antikoerper, wu:fj51c01 antikoerper, zgc:103705 antikoerper, DKFZp469E061 antikoerper, CMS antikoerper, AL024079 antikoerper, C78928 antikoerper, METS-1 antikoerper, Mets1 antikoerper, CD2-associated protein L homeolog antikoerper, CD2 associated protein antikoerper, CD2-associated protein antikoerper, cd2ap.L antikoerper, CD2AP antikoerper, cd2ap antikoerper, Cd2ap antikoerper

Hintergrund:

Description: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed:15800069). Plays a role in epithelial cell junctions formation (PubMed:22891260).

Gene: CD2AP

Molekulargewicht: 74 kDa

Gen-ID: 23607

UniProt: Q9Y5K6