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Fibrinogen beta Chain Antikörper (C-Term)

FGB Reaktivität: Human, Maus WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258456
  • Target Alle Fibrinogen beta Chain (FGB) Antikörper anzeigen
    Fibrinogen beta Chain (FGB)
    Bindungsspezifität
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 56
    • 16
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 55
    • 14
    • 1
    Kaninchen
    Klonalität
    • 56
    • 14
    Polyklonal
    Konjugat
    • 37
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert
    Applikation
    • 50
    • 25
    • 22
    • 11
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    FGB Antibody detects endogenous levels of total FGB.
    Homologie
    Zebrafish,Bovine,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human FGB, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product FGB Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Fibrinogen beta Chain (FGB)
    Andere Bezeichnung
    FGB (FGB Produkte)
    Synonyme
    FGB antikoerper, 2510049G14Rik antikoerper, DKFZp470D0312 antikoerper, LOC100223598 antikoerper, fibrinogen antikoerper, Ab1-216 antikoerper, Ac1-581 antikoerper, wu:fa55c11 antikoerper, zgc:77116 antikoerper, fgb antikoerper, fibrinogen beta chain antikoerper, fibrinogen beta chain L homeolog antikoerper, FGB antikoerper, Fgb antikoerper, fgb antikoerper, fgb.L antikoerper
    Hintergrund

    Description: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

    Gene: FGB

    Molekulargewicht
    56 kDa
    Gen-ID
    2244
    UniProt
    P02675
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