MRPL41 Antikörper (C-Term)

Produktnummer ABIN6258452

Produktdetails anti-MRPL41 Antikörper

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: MRPL41 Antibody detects endogenous levels of total MRPL41.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MRPL41, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Andere Bezeichnung: MRPL41 (MRPL41 Produkte)

Synonyme: BcDNA:RE19416 antikoerper, CG12954 antikoerper, Dmel\\CG12954 antikoerper, YmL27 antikoerper, MRP-L27 antikoerper, Rpml27 antikoerper, zgc:112362 antikoerper, BMRP antikoerper, MRPL27 antikoerper, RPML27 antikoerper, L41mt-A antikoerper, MRP-L41-A antikoerper, bmrp antikoerper, mrp-l27 antikoerper, mrpl27 antikoerper, mrpl41 antikoerper, mrpl41-a antikoerper, mrpl41-b antikoerper, pig3 antikoerper, rpml27 antikoerper, mitochondrial ribosomal protein L41 antikoerper, 39S ribosomal protein L41, mitochondrial antikoerper, mitochondrial ribosomal protein L41 L homeolog antikoerper, mRpL41 antikoerper, Mrpl41 antikoerper, MRPL41 antikoerper, mrpl41 antikoerper, LOC724790 antikoerper, mrpl-41 antikoerper, mrpl41.L antikoerper

Hintergrund:

Description: Component of the mitochondrial ribosome large subunit (PubMed:25278503, PubMed:25838379). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796).

Gene: MRPL41

Molekulargewicht: 21 kDa

Gen-ID: 64975

UniProt: Q8IXM3

Pathways: p53 Signalweg