ZC3H8 Antikörper (Internal Region)

Produktnummer ABIN6258445

Produktdetails anti-ZC3H8 Antikörper

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZC3H8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: ZC3H8 Antibody detects endogenous levels of total ZC3H8.

Homologie: Pig,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZC3H8, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ZC3H8

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Andere Bezeichnung: ZC3H8 (ZC3H8 Produkte)

Synonyme: Zc3hdc8 antikoerper, DKFZp459D018 antikoerper, AU020882 antikoerper, E130108N08Rik antikoerper, Fliz1 antikoerper, ZC3HDC8 antikoerper, zinc finger CCCH type containing 8 antikoerper, zinc finger CCCH-type containing 8 antikoerper, Zc3h8 antikoerper, ZC3H8 antikoerper

Hintergrund:

Description: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Gene: ZC3H8

Molekulargewicht: 40 kDa

Gen-ID: 84524

UniProt: Q8N5P1