KCNQ4 Antikörper (C-Term)

Produktnummer ABIN6258250

Produktdetails anti-KCNQ4 Antikörper

Target: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNQ4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: KCNQ4 Antibody detects endogenous levels of total KCNQ4.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNQ4, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu KCNQ4

Target: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Andere Bezeichnung: KCNQ4 (KCNQ4 Produkte)

Synonyme: KCNQ4 antikoerper, k(v)7.4 antikoerper, kv7.4 antikoerper, DFNA2 antikoerper, DFNA2A antikoerper, KV7.4 antikoerper, potassium voltage-gated channel subfamily Q member 4 antikoerper, potassium channel, voltage gated KQT-like subfamily Q, member 4 antikoerper, potassium voltage-gated channel, subfamily Q, member 4 antikoerper, KCNQ4 antikoerper, kcnq4 antikoerper, Kcnq4 antikoerper

Hintergrund:

Description: Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.

Gene: KCNQ4

Molekulargewicht: 80 kDa

Gen-ID: 9132

UniProt: P56696

Pathways: Sensory Perception of Sound