SARNP Antikörper (Internal Region)

Produktnummer ABIN6258229

Produktdetails anti-SARNP Antikörper

Target: SARNP (SAP Domain Containing Ribonucleoprotein (SARNP))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: CIP29 Antibody detects endogenous levels of total CIP29.

Homologie: Pig,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CIP29, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SARNP

Target: SARNP (SAP Domain Containing Ribonucleoprotein (SARNP))

Andere Bezeichnung: SARNP (SARNP Produkte)

Synonyme: CIP29 antikoerper, HCC1 antikoerper, HSPC316 antikoerper, THO1 antikoerper, 1110005A23Rik antikoerper, Cip29 antikoerper, RGD1305692 antikoerper, cip29 antikoerper, 1110005a23rik antikoerper, wu:fb11c11 antikoerper, zgc:109957 antikoerper, SAP domain containing ribonucleoprotein antikoerper, SAP domain containing ribonucleoprotein S homeolog antikoerper, SARNP antikoerper, Sarnp antikoerper, sarnp antikoerper, sarnp.S antikoerper

Hintergrund:

Description: Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

Gene: SARNP

Molekulargewicht: 30 kDa

Gen-ID: 84324

UniProt: P82979