GRIN2D Antikörper (Internal Region)

Produktnummer ABIN6258225

Produktdetails anti-GRIN2D Antikörper

Target: GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2D Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: GRIN2D Antibody detects endogenous levels of total GRIN2D.

Homologie: Pig,Bovine,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GRIN2D, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GRIN2D

Target: GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))

Andere Bezeichnung: GRIN2D (GRIN2D Produkte)

Synonyme: nr2d antikoerper, EB11 antikoerper, GluN2D antikoerper, NMDAR2D antikoerper, NR2D antikoerper, glutamate ionotropic receptor NMDA type subunit 2D antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2D antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog antikoerper, glutamate receptor, ionotropic, NMDA2D (epsilon 4) antikoerper, GRIN2D antikoerper, grin2d.L antikoerper, grin2d antikoerper, Grin2d antikoerper

Hintergrund:

Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750).

Gene: GRIN2D

Molekulargewicht: 170 kDa

Gen-ID: 2906

UniProt: O15399

Pathways: Synaptic Membrane