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BCOR Antikörper (Internal Region)

BCOR Reaktivität: Human, Maus ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257962
  • Target Alle BCOR Antikörper anzeigen
    BCOR (BCL6 Co-Repressor (BCOR))
    Bindungsspezifität
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 30
    • 14
    • 1
    Human, Maus
    Wirt
    • 26
    • 4
    • 1
    Kaninchen
    Klonalität
    • 30
    • 1
    Polyklonal
    Konjugat
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BCOR Antikörper ist unkonjugiert
    Applikation
    • 16
    • 13
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    BCOR Antibody detects endogenous levels of total BCOR.
    Homologie
    Pig,Bovine,Sheep,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human BCOR, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product BCOR Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    BCOR (BCL6 Co-Repressor (BCOR))
    Andere Bezeichnung
    BCOR (BCOR Produkte)
    Synonyme
    ANOP2 antikoerper, MAA2 antikoerper, MCOPS2 antikoerper, BCOR antikoerper, RGD1562735 antikoerper, 5830466J11Rik antikoerper, 8430401K06Rik antikoerper, BcorR antikoerper, D930024N20Rik antikoerper, mKIAA1575 antikoerper, BCL6 corepressor antikoerper, BCL6 co-repressor antikoerper, BCL6 interacting corepressor antikoerper, BCOR antikoerper, bcor antikoerper, Bcor antikoerper
    Hintergrund

    Description: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).

    Gene: BCOR

    Molekulargewicht
    192 kDa
    Gen-ID
    54880
    UniProt
    Q6W2J9
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