CRHR2 Antikörper (Internal Region)

Produktnummer ABIN6257813

Produktdetails anti-CRHR2 Antikörper

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRHR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CRHR2 Antibody detects endogenous levels of total CRHR2.

Homologie: Pig,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CRHR2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Andere Bezeichnung: CRHR2 (CRHR2 Produkte)

Synonyme: CRF-RB antikoerper, CRF2 antikoerper, CRFR2 antikoerper, HM-CRF antikoerper, CRF-R2 antikoerper, CRFR2alpha antikoerper, CRFR2beta antikoerper, Crfr2 antikoerper, Crf2r antikoerper, CRH-R2 antikoerper, crhr2-A antikoerper, corticotropin releasing hormone receptor 2 antikoerper, corticotropin releasing hormone receptor 2 S homeolog antikoerper, CRHR2 antikoerper, Crhr2 antikoerper, crhr2.S antikoerper

Hintergrund:

Description: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

Gene: CRHR2

Molekulargewicht: 48 kDa

Gen-ID: 1395

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour