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UBASH3A Antikörper (Internal Region)

UBASH3A Reaktivität: Human ELISA, WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257504
  • Target Alle UBASH3A Antikörper anzeigen
    UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 31
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 4
    • 2
    Kaninchen
    Klonalität
    • 40
    • 3
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBASH3A Antikörper ist unkonjugiert
    Applikation
    • 30
    • 25
    • 4
    • 3
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    UBASH3A Antibody detects endogenous levels of total UBASH3A.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human UBASH3A, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product UBASH3A Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
    Andere Bezeichnung
    UBASH3A (UBASH3A Produkte)
    Synonyme
    UBASH3A antikoerper, CLIP4 antikoerper, STS-2 antikoerper, TULA antikoerper, TULA-1 antikoerper, 5830413C03Rik antikoerper, C330001M22 antikoerper, Sts-2 antikoerper, ubiquitin associated and SH3 domain containing A antikoerper, ubiquitin associated and SH3 domain containing, A antikoerper, UBASH3A antikoerper, Ubash3a antikoerper
    Hintergrund

    Description: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral  pH . May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

    Gene: UBASH3A

    Molekulargewicht
    74 kDa
    Gen-ID
    53347
    UniProt
    P57075
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