RBM5 Antikörper (N-Term)

Produktnummer ABIN6257462

Produktdetails anti-RBM5 Antikörper

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: RBM5 Antibody detects endogenous levels of total RBM5.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RBM5, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RBM5

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Andere Bezeichnung: RBM5 (RBM5 Produkte)

Synonyme: wu:fc25a08 antikoerper, wu:fe06f12 antikoerper, g15 antikoerper, h37 antikoerper, luca15 antikoerper, rbm5 antikoerper, rmb5 antikoerper, RBM5 antikoerper, G15 antikoerper, LUCA15 antikoerper, RMB5 antikoerper, D030069N10Rik antikoerper, RNA binding motif protein 5 antikoerper, RNA binding motif protein 5 S homeolog antikoerper, RNA binding motif protein 5 L homeolog antikoerper, rbm5 antikoerper, rbm5.S antikoerper, RBM5 antikoerper, rbm5.L antikoerper, Rbm5 antikoerper

Hintergrund:

Description: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

Gene: RBM5

Molekulargewicht: 92 kDa

Gen-ID: 10181

UniProt: P52756

Pathways: Ribonucleoprotein Complex Subunit Organization