KCNK4 Antikörper (C-Term)

Produktnummer ABIN6257437

Produktdetails anti-KCNK4 Antikörper

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: KCNK4 Antibody detects endogenous levels of total KCNK4.

Homologie: Pig,Bovine,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNK4, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu KCNK4

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Andere Bezeichnung: KCNK4 (KCNK4 Produkte)

Synonyme: K2p4.1 antikoerper, TRAAK antikoerper, TRAAK1 antikoerper, MLZ-622 antikoerper, TRAAKt antikoerper, Tex40 antikoerper, KT4.1 antikoerper, potassium two pore domain channel subfamily K member 4 antikoerper, potassium channel, subfamily K, member 4 antikoerper, KCNK4 antikoerper, Kcnk4 antikoerper

Hintergrund:

Description: Voltage-insensitive potassium channel (PubMed:22282805). Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157). Channel opening is triggered by raising the intracellular  pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro), raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity).

Gene: KCNK4

Molekulargewicht: 45 kDa

Gen-ID: 50801

UniProt: Q9NYG8