DYRK1B Antikörper (Internal Region)

Produktnummer ABIN6257023

Produktdetails anti-DYRK1B Antikörper

Target: DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYRK1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: DYR1B Antibody detects endogenous levels of total DYR1B.

Homologie: Pig,Bovine,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DYR1B, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DYRK1B

Target: DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

Andere Bezeichnung: DYRK1B (DYRK1B Produkte)

Synonyme: DYRK1B antikoerper, MIRK antikoerper, Mirk antikoerper, DYRK1A antikoerper, dual specificity tyrosine phosphorylation regulated kinase 1B antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b antikoerper, DYRK1B antikoerper, Dyrk1b antikoerper

Hintergrund:

Description: Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).

Gene: DYRK1B

Molekulargewicht: 70 kDa

Gen-ID: 9149

UniProt: Q9Y463