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PFKL Antikörper (C-Term)

PFKL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257021
  • Target Alle PFKL Antikörper anzeigen
    PFKL (Phosphofructokinase, Liver (PFKL))
    Bindungsspezifität
    • 9
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 48
    • 24
    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 45
    • 5
    Kaninchen
    Klonalität
    • 46
    • 4
    Polyklonal
    Konjugat
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PFKL Antikörper ist unkonjugiert
    Applikation
    • 38
    • 22
    • 22
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    K6PL Antibody detects endogenous levels of total K6PL.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human K6PL, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PFKL Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PFKL (Phosphofructokinase, Liver (PFKL))
    Andere Bezeichnung
    PFKL (PFKL Produkte)
    Synonyme
    PFK-B antikoerper, AA407869 antikoerper, phosphofructokinase, liver type antikoerper, phosphofructokinase, liver, B-type antikoerper, PFKL antikoerper, Pfkl antikoerper
    Hintergrund

    Description: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity).

    Gene: PFKL

    Molekulargewicht
    85 kDa
    Gen-ID
    5211
    UniProt
    P17858
    Pathways
    Negative Regulation of Hormone Secretion, Warburg Effekt
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