AIM2 Antikörper (Internal Region)
-
- Target Alle AIM2 Antikörper anzeigen
- AIM2 (Absent in Melanoma 2 (AIM2))
-
Bindungsspezifität
- Internal Region
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser AIM2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- AIM2 Antibody detects endogenous levels of total AIM2.
- Homologie
- Horse
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human AIM2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product AIM2 Primärantikörper
-
anti-Absent in Melanoma 2 (AIM2) (AA 1-195) antibody
AIM2 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 3C4G11 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-50) antibodyAIM2 Reaktivität: Human WB, ELISA, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 81-326) antibodyAIM2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 4-32), (N-Term) antibodyAIM2 Reaktivität: Human WB, FACS, IF Wirt: Kaninchen Polyclonal RB23659 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-260) antibodyAIM2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 14-215) antibodyAIM2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 255-354) antibodyAIM2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
-
- Target
- AIM2 (Absent in Melanoma 2 (AIM2))
- Andere Bezeichnung
- AIM2 (AIM2 Produkte)
- Synonyme
- AIM2 antikoerper, PYHIN4 antikoerper, Gm1313 antikoerper, Ifi210 antikoerper, absent in melanoma 2 antikoerper, AIM2 antikoerper, Aim2 antikoerper
- Hintergrund
-
Description: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
Gene: AIM2
- Molekulargewicht
- 39 kDa
- Gen-ID
- 9447
- UniProt
- O14862
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
-
