PPP2R5B Antikörper (C-Term)

Produktnummer ABIN6243837

Produktdetails anti-PPP2R5B Antikörper

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Bindungsspezifität: AA 466-500, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPP2R5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 466-500 amino acids from the C-terminal region of human PPP2R5B.

Klon: RB51478

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu PPP2R5B

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Andere Bezeichnung: PPP2R5B (PPP2R5B Produkte)

Synonyme: B56B antikoerper, PR61B antikoerper, B'beta antikoerper, BC026670 antikoerper, PPP2R5B antikoerper, ppp2r5e antikoerper, protein phosphatase 2 regulatory subunit B'beta antikoerper, protein phosphatase 2, regulatory subunit B', beta antikoerper, protein phosphatase 2A regulatory subunit B' antikoerper, protein phosphatase 2 regulatory subunit B', beta antikoerper, protein phosphatase 2 regulatory subunit Bbeta antikoerper, PPP2R5B antikoerper, Ppp2r5b antikoerper, ppp2r5b antikoerper, ppp2r5b.L antikoerper, PPP2R2B antikoerper

Hintergrund: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.

Molekulargewicht: 57393

UniProt: Q15173

Pathways: PI3K-Akt Signalweg, ER-Nucleus Signaling