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RORC Antikörper (Internal Region)

RORC Reaktivität: Human, Maus, Rind (Kuh), Hund WB, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN615977
  • Target Alle RORC Antikörper anzeigen
    RORC (RAR-Related Orphan Receptor C (RORC))
    Bindungsspezifität
    • 16
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-212, Internal Region
    Reaktivität
    • 97
    • 55
    • 23
    • 9
    • 8
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Rind (Kuh), Hund
    Wirt
    • 80
    • 17
    • 2
    • 1
    • 1
    • 1
    Ziege
    Klonalität
    • 83
    • 19
    Polyklonal
    Konjugat
    • 54
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser RORC Antikörper ist unkonjugiert
    Applikation
    • 81
    • 37
    • 24
    • 24
    • 15
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequenz
    CHLEYSPERG KAE
    Spezifität
    This antibody is expected to recognize both reported isoforms (NP_005051.2, NP_001001523.1).
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Canine (Dog) and Cow.
    Species reactivity (tested):Human.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_005051.2, NP_001001523.1. Genename: RORC
    Top Product
    Discover our top product RORC Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    RORC (RAR-Related Orphan Receptor C (RORC))
    Andere Bezeichnung
    ROR-gamma / RORC (RORC Produkte)
    Synonyme
    NR1F3 antikoerper, RORG antikoerper, RZR-GAMMA antikoerper, RZRG antikoerper, TOR antikoerper, Nr1f3 antikoerper, RORgamma antikoerper, Thor antikoerper, RAR related orphan receptor C antikoerper, RAR-related orphan receptor C antikoerper, RAR-related orphan receptor gamma antikoerper, RORC antikoerper, Rorc antikoerper
    Hintergrund
    ROR-gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR-gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR-gamma shares 50 to 51 % sequence identity with RORA and RORB and is 88 % identical to mouse ROR-gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.Synonyms: NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RORG, RZRG, Retinoid-related orphan receptor-gamma
    Gen-ID
    6097
    NCBI Accession
    NP_001001523
    UniProt
    P51449
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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