VRK1 Antikörper (AA 257-396)

Produktnummer ABIN6150147

Produktdetails anti-VRK1 Antikörper

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Bindungsspezifität: AA 257-396

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GHLPWEDNLK DPKYVRDSKI RYRENIASLM DKCFPEKNKP GEIAKYMETV KLLDYTEKPL YENLRDILLQ GLKAIGSKDD GKLDLSVVEN GGLKAKTITK KRKKEIEESK EPGVEDTEWS NTQTEEAIQT RSRTRKRVQK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-396 of human VRK1 (NP_003375.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu VRK1

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Andere Bezeichnung: VRK1 (VRK1 Produkte)

Synonyme: vrk1 antikoerper, MGC64390 antikoerper, MGC75762 antikoerper, VRK1 antikoerper, PCH1 antikoerper, PCH1A antikoerper, 51PK antikoerper, wu:fe16f06 antikoerper, zgc:56266 antikoerper, vaccinia related kinase 1 L homeolog antikoerper, vaccinia related kinase 1 antikoerper, Serine/threonine-protein kinase VRK1 antikoerper, vrk1.L antikoerper, vrk1 antikoerper, VRK1 antikoerper, vrk-1 antikoerper, Vrk1 antikoerper

Hintergrund: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.,VRK1,PCH1,PCH1A,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,VRK1

Molekulargewicht: 45 kDa

Gen-ID: 7443

UniProt: Q99986