TSH receptor Antikörper (AA 21-253)

Produktnummer ABIN6149622

Produktdetails anti-TSH receptor Antikörper

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Bindungsspezifität: AA 21-253

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSH receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GMGCSSPPCE CHQEEDFRVT CKDIQRIPSL PPSTQTLKLI ETHLRTIPSH AFSNLPNISR IYVSIDVTLQ QLESHSFYNL SKVTHIEIRN TRNLTYIDPD ALKELPLLKF LGIFNTGLKM FPDLTKVYST DIFFILEITD NPYMTSIPVN AFQGLCNETL TLKLYNNGFT SVQGYAFNGT KLDAVYLNKN KYLTVIDKDA FGGVYSGPSL LLPLGRKSLS FETQKAPRSS MPS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR (NP_001018046.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-TSH receptor Antikörper (ABIN6149622)

Yang, Yi, Zhang, He, He, Wu, Xu, Li, Fan, Zhu, Xue, Zhou: "Generation and characterization of a hypothyroidism rat model with truncated thyroid stimulating hormone receptor." in: Scientific reports, Vol. 8, Issue 1, pp. 4004, (2018) (PubMed).

Details zu TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Andere Bezeichnung: TSHR (TSHR Produkte)

Synonyme: CHNG1 antikoerper, LGR3 antikoerper, hTSHR-I antikoerper, AI481368 antikoerper, hypothroid antikoerper, hyt antikoerper, pet antikoerper, TSHRA antikoerper, TSH-R antikoerper, thyroid stimulating hormone receptor antikoerper, tshr antikoerper, TSHR antikoerper, Tshr antikoerper

Hintergrund: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.,TSHR,CHNG1,LGR3,hTSHR-I,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,TSHR

Molekulargewicht: 28 kDa/30 kDa/86 kDa

Gen-ID: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis